Bioactive Small Molecules
Cayman Chemical ANTIBODY TenovIn-3 500ug
A small molecule activator of p53; increases p53 activity in MCF-7 cells at 10 µM; increases the level of K40-acetylated α-tubulin in H1299 cells; inhibits SIRT2 protein deacetylase activity
Medchemexpress LLC 4-nitrocatechol | 3316-09-4 | MFCD00007242 | 99.7% | 155.11 | C6H5NO4 | 5 G
4-nitrocatechol is a small-molecule lipoxygenase inhibitor supplied for research use. It has CAS number 3316-09-4, molecular formula C6H5NO4, and molecular weight 155.11. The material is supplied as a powder with reported purity of 99.73% and is available in multiple pack sizes including 5 g. Store powder at -20°C for long-term storage; in solution, store at -80°C for longer stability.
- potent lipoxygenase inhibitor for biochemical studies.
- high reported purity for analytical work.
- available in convenient small-scale pack sizes for lab use.
- stable as a dry powder under frozen storage.
- intended for research use only; not for human consumption.
Medchemexpress LLC 3BrB-PP1 10mg | 956025-99-3 | 10 MG
3BrB-PP1 is an ATP-analog research compound used to selectively inhibit analog-sensitive kinases in biochemical and cell-based assays. It is supplied as a 10 mg solid for research use.
- Purity 99.0%
- Molecular formula C16H18BrN5
- Molecular weight 360.25 g/mol
- Soluble in DMSO at 100 mg/mL
- Suitable for in vitro biochemical and cell-based kinase assays
Cayman Chemical ANTIBODY Prasugrel 100mg
A prodrug form of R-99224; inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma at 0.3 and 3 mg/kg; prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats
Cayman Chemical HalofugInonhydrochlorIde 5mg
A halogenated derivative of febrifugine that down-regulates Smad3, blocking TGF-β signaling relevant to fibrosis and tumor progression in a variety of different models; competitively inhibits prolyl-tRNA synthetase (Ki = 18.3 nM), preventing the differentiation of TH17 cells and blunting an autoimmune response
Cayman Chemical ngIotensIn IIIhumnmouse 5mg
An agonist at AT1 and AT2 receptors, with a 30-fold higher affinity for AT2
Medchemexpress LLC DOTA-NOC | 619300-53-7 | 99.2% | 1455.70 | 1 MG
DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand for somatostatin receptor subtypes 2, 3, and 5. This compound is valuable for labeling with various radiometals and for advancing radiopeptide imaging techniques. It also serves as a key component in the synthesis and research of Radionuclide-Drug Conjugates (RDCs).
- High-affinity ligand for somatostatin receptor subtypes 2, 3, and 5
- Can be used for labeling with various radiometals
- Suitable for the development of radiopeptide imaging
- Utilized for the synthesis and research of radionuclide-drug conjugates (RDCs)
Medchemexpress LLC 2-bromo-1-(4-hydroxyphenyl)propan-1-one | 53946-87-5 | MFCD09743923 | 1g
2-Bromo-1-(4-hydroxyphenyl)propan-1-one is a drug impurity
Cayman Chemical JNJ-26854165 1mg
An antagonist of MDM2 that suppresses the growth of cancer cell lines expressing wild-type p53 (IC50 values range from 240-440 nM); orally bioavailable, having anti-proliferation as well as apoptotic actions in various tumor models; affects multiple signaling pathways
Apexbio Technology LLC Bafetinib (INNO-406) 887650-05-7 100mg
Bafetinib (INNO-406 CAS 887650-05-7) is a selective dual inhibitor of Bcr-Abl and Lyn tyrosine kinases It demonstrates potent inhibition of Bcr-Abl (IC50 5 8 nM) and Lyn (IC50 19 nM) and suppresses Bcr-Abl autophosphorylation Bafetinib exhibits activity against Bcr-Abl-expressing cell lines such as K562 and 293T (IC50 11 nM and 22 nM respectively) and inhibits the proliferation of Bcr-Abl-positive leukemia cells including those harboring certain resistance mutations (e g M244V G250E Y253F F317L) but is inactive against T315I mutants In mouse tumor models bafetinib effectively suppresses tumor growth This compound is valuable in leukemia research particularly for studies on Bcr-Abl kinase inhibition and resistance mechanisms
Cayman Chemical DemethoxyvIrIdIol 5mg
A mycotoxin; induces lethality in day-old cockerels (LD50 = 4.2 mg/kg); a PI3K inhibitor
Medchemexpress LLC Malonyl coenzyme A lithium | 108347-84-8 | MFCD00057769 | 98.0% | 860.6 g/mol | C24H38LiN7O19P3S | 5 MG
Malonyl CoA lithium is the lithium salt form of malonyl coenzyme A used as a biochemical reagent to modulate mitochondrial fatty acid metabolism. It functions as an inhibitor of carnitine palmitoyl transferase 1 (CPT1) and is intended for research use in studies of lipid metabolism and energy homeostasis.
- Inhibitor of carnitine palmitoyl transferase 1 (CPT1).
- Modulates fatty acid oxidation in cellular and biochemical assays.
- Provided as the lithium salt to aid solubility in aqueous systems.
- Useful for studies of mitochondrial metabolism and lipid regulation.
- Accompanied by datasheet, certificate of analysis, and safety data sheet.
Cayman Chemical DeterenolhydrochlorIde 5mg
A β-adrenergic receptor agonist; increases tension in isolated right and left guinea pig atria and trachea (IC50s = 0.411, 1.44, and 8.37 µM, respectively), which endogenously express β-ARs, but has no effect on isolated rabbit aortic strips, which express α-ARs; induces lipolysis in human adipocytes
Medchemexpress LLC Azd-co-ph-peg4-ph-co-azd | 2569143-72-0 | MFCD00231029 | 96.0% | C26H28N2O8 | 10MG
AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker developed for synthesis of antibody-siRNA conjugates. It is supplied as a white to off-white solid (C26H28N2O8; MW 496.51; CAS 2569143-72-0) with reported purity of approximately 96%, and is soluble in DMSO with recommended formulations for in vivo use.
- Bis-β-lactam linker suitable for antibody-siRNA conjugation.
- High reported purity (~96%) supporting experimental reproducibility.
- Solid form simplifies storage and handling.
- Soluble in DMSO (50 mg/mL) for in vitro applications.
- Includes recommended in vivo formulation options for dosing studies.
- Available in small pack sizes appropriate for research use.